منابع مشابه
Stem cell approaches for vocal fold regeneration.
OBJECTIVES/HYPOTHESIS Current interventions in the management of vocal fold (VF) dysfunction focus on conservative and surgical approaches. However, the complex structure and precise biomechanical properties of the human VF mean that these strategies have their limitations in clinical practice and in some cases offer inadequate levels of success. Regenerative medicine is an exciting development...
متن کاملAdipose-derived stem cells versus bone marrow-derived stem cells for vocal fold regeneration.
OBJECTIVES/HYPOTHESIS Vocal fold scarring presents therapeutic challenges. Recently, cell therapy with mesenchymal stromal cells has become a promising approach. The aim of this study was to compare the therapeutic potential of adipose-derived stem cells (ASC) with bone marrow-derived stem cells (BMSC) for vocal fold regeneration. STUDY DESIGN Prospective animal experiments with controls. M...
متن کاملCharacterization of mesenchymal stem cells from human vocal fold fibroblasts.
OBJECTIVES/HYPOTHESIS Mesenchymal stem cells (MSCs) originally isolated from bone marrow (BM), are fibroblast-looking cells that are now assumed to be present in the stromal component of many tissues. MSCs are characterized by a certain set of criteria, including their growth culture characteristics, a combination of cell surface markers, and the ability to differentiate along multiple mesenchy...
متن کاملRegeneration of Vocal Fold Mucosa Using Tissue-Engineered Structures with Oral Mucosal Cells
OBJECTIVES Scarred vocal folds result in irregular vibrations during phonation due to stiffness of the vocal fold mucosa. To date, a completely satisfactory corrective procedure has yet to be achieved. We hypothesize that a potential treatment option for this disease is to replace scarred vocal folds with organotypic mucosa. The purpose of this study is to regenerate vocal fold mucosa using a t...
متن کاملCytoskeleton of newborn vocal fold stellate cells.
OBJECTIVES/HYPOTHESIS Vocal fold stellate cells (VFSCs) in the human maculae flavae located at both ends of the vocal fold mucosa are inferred to be involved in the metabolism of extracellular matrices of the vocal fold mucosa. Tension caused by phonation (vocal fold vibration) likely regulates the behavior of the VFSCs in the human maculae flava. Tensile and compressive strains have direct eff...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Japan Journal of Logopedics and Phoniatrics
سال: 2015
ISSN: 0030-2813,1884-3646
DOI: 10.5112/jjlp.56.209